I’ve rarely met an unfriendly blogger. I’ve met extremely busy bloggers, but I can’t imagine any blogger I’ve met who knows a thing or two honestly wants to withhold major blogging secrets or not reach out and say hello.
Don’t think of bloggers with big audiences as anyone different than you. If you have a good question, just ask. Get to the point, and don’t expect an answer right away, but don’t let intimidation or cynicism stop you from initiating a conversation.
Also, make friends. Blogging is much more fun when you make blogging friends. Email or tweet a blogger, and see if you hit it off.
A hint on this last tip: Reach out to a blogger that seems to have about the same size audience, or who writes about the same topic as you. That way, you can share ideas and experiences as you journey together. (But you never know, really — Alli and I are fantastic friends, yet our blogs could not be more different.)